- 2007: Reprised role of Marge Simpson for "The Simpsons Movie" an animated feature based on the long running Fox series
- 2006: Cast opposite Adam Sandler in the comedy "Click" directed by Frank Coraci
- 1997: Co-starred in Woody Allen's "Deconstructing Harry"
- 1996: Re-teamed with Tracy Ullman on the HBO series "Tracey Takes On..."
- 1995: Appeared in the comedy "Forget Paris" with Debra Winger and Billy Crystal
- 1994: Co-starred in the Woody Allen film "Don't Drink the Water"
- 1992: Starred in the Nora Ephron comedy drama "This Is My Life"
- 1990: Played a nurse opposite Robin Williams in the film "Awakenings"
- 1990: Provides the voice of Marge Simpson as well as her two sisters Patty and Selma on "The Simpsons" (Fox)
- 1981: Film debut in "National Lampoon Goes to the Movies"
- 1975: TV debut on ABC Afternoon Playbreak "The Girl Who Couldn't Lose"
- 1975: TV movie debut in "Katherine" (ABC)
- 1974: Was performing in an Equity waiver theater production in Los Angeles while working days as a typist at UCLA architecture school when David Davis asked her to read for role of Brenda Morgenstern on new TV series, "Rhoda"
- 1974: First professional acting work, costarring as Valarie Harper's sister Brenda Morgenstern on TV series, "Rhoda"
- Raised in Burbank and Beverly Hills, California
- Was a featured regular on "The Tracey Ullman Show" (Fox)




