Family
- father Jose Dominguez: Reportedly worked for Fascist dictator Francisco Franco's secret police; died Feb. 2, 2008 at age 87
- mother Ana Banderas:
- brother Francisco Dominguez Banderas: Looks after brother's business interests in Spain
- daughter Stella del Carmen Banderas Griffith: Born Sep. 24, 1996; mother, Melanie Griffith
Companions
- wife Melanie Griffith: met on set of "Two Much" in January 1995; married in London on May 14, 1996; reportedly separated Decemebr 2002
