Family
- father : played tuba with Tony Pastor and Rosemary Clooney
- mother : amateur violinist
- brother Jeff D'Angelo: in Blue Martini jazz band with sister
- son Anton Pacino: born on January 25, 2001; fraternal twin of Olivia; father, Al Pacino
- daughter Olivia Pacino: born on January 25, 2001; fraternal twin of Anton; father, Al Pacino
Companions
- Companion Scott Baio: born in 1961; dated briefly in the 1990s; broke up over age difference
- Al Pacino: together from c. 1997
- Anton Furst: worked on "Batman" and "Full Metal Jacket"; committed suicide soon after their breakup
- Milos Foreman: met during filming of "Hair"
- Neil Jordan: together c. 1985 to 1991; directed D'Angelo in "The Miracle"
- Scott Baio: born in 1961; dated briefly in the 1990s; broke up over age difference
