- 2009: Co-starred with Michelle Pfeiffer in Stephen Frears' "Cheri"
- 2008: Re-teamed with "Titanic" co-stars, Leonardo DiCaprio and Kate Winslet for "Revolutionary Road"
- 2008: Cast as the Secretary of Defense in the remake of the 1951 science fiction movie "The Day the Earth Stood Still"
- 2007: Voiced a Bee in the computer-animated "Bee Movie"
- 2007: Cast as Mother Claus opposite Vince Vaughn and Paul Giamatti in the comedy "Fred Claus"
- 2006: Earned an Emmy nomination for Best Actress in a Miniseries or Movie for "Ambulance Girl"
- 2006: Voiced Bitsy the cow in live-action/computer-animated feature film "Charlotte's Web," based on the book by E.B. White
- 2005: Cast in Rob Reiner's "Rumor Has It" with Kevin Costner and Jennifer Aniston
- 2005: Earned an Emmy nomination for her role as FDR's physical therapist in the HBO Films original movie "Warm Springs"
- 2004: Starred with Brittany Murphy in the romantic comedy "Little Black Book"
- 2004: Played Queen Victoria in the Disney live action feature "Around the World in 80 Days" based on the classical novel by Jules Verne
- 2002: Played a fan who helps the male lover of a murdered pop star investigate the killing in "Who Shot Victor Fox?"
- 2002: Had a recurring role as Bettina, in the acclaimed HBO series "Six Feet Under"; also directed episodes; earned an Emmy nomination in 2003 for Outstanding Guest Actress
- 2002: Co-starred in the television feature "My Sister's Keeper"; received a SAG nomination Best Actress in a TV movie
- 2002: Had a bravura turn as the future in-law to Jack Nicholson in "About Schmidt"; earned Golden Globe, SAG and Oscar nominations for her supporting role
- 2001: Portrayed the mother of the James brothers in the revisionist Western "American Outlaws"
- 1999: Helmed the TV-movie "Dash & Lilly" (A&E), about Dashiell Hammett and Lillian Hellman; received Emmy nomination
- 1999: Starred as Miss Hannigan in Disney's remake of "Annie" (ABC); received Emmy nomination
- 1998: Delivered a scene-stealing supporting turn as a political advisor Libby Holden in "Primary Colors"
- 1998: Portrayed Adam Sandler's mother in the suprise hit "The Waterboy"
- 1998: Directed an episode of the HBO series "Oz"
- 1997: Directed the failed pilot "Fargo"
- 1997: Portrayed 'The Unsinkable Molly Brown' in James Cameron's blockbuster "Titanic"
- 1996: Portrayed Jay Leno's manager Helen Kushnick in the HBO movie "The Late Shift"
- 1996: Cast as the tenacious police woman investigating the disappearance of the school's headmaster in the remake of "Diabolique"
- 1996: Helmed episodes of "Homicide: Life on the Street" and "NYPD Blue"
- 1995: Starred as the title character, a woman accused of murder, in the feature adaptation of Stephen King's "Dolores Claiborne"
- 1995: TV directorial debut, the PBS production "Talking With"; also acted in one segment
- 1994: Made uncredited appearance in the ABC miniseries "Stephen King's The Stand"
- 1992: Played supporting role in "Prelude to a Kiss"
- 1991: Co-starred with Jessica Tandy in "Fried Green Tomatoes"
- 1990: Breakthrough screen performance as obsessed fan Annie Wilkes in "Misery"
- 1988: Replaced Amy Irving in the Off-Broadway production of Athol Fugard's play "The Road to Mecca"; reprised role in 1981 feature version
- 1988: Appeared in a two-part episode of the ABC drama "China Beach"
- 1987: Starred Off-Broadway and in Los Angeles (1988) in "Frankie and Johnny in the Clair de Lune" in a role written for her by playwright Terrence McNally
- 1987: Had supporting role in the CBS miniseries "Murder Ordained"
- 1986: TV-movie debut, "Johnny Bull" (ABC)
- 1984: Played Belle, the cellmate of Erica Kane, on the ABC daytime drama "All My Children"
- 1983: Starred on Broadway in "'night Mother"; received Tony nomination for her portrayal of a depressed woman bent on suicide
- 1982: Originated role of Stella May in the short-lived Broadway production of "Come Back to the Five and Dime, Jimmy Dean, Jimmy Dean"; staged by Robert Altman; reprised part in Altman's film version
- 1981: Appeared in the Actors Theatre of Louisville production of "Extremities"
- 1980: Broadway debut in support of Jane Alexander in the short-lived production "Goodbye Fidel"
- 1978: Was a member of the company of the Actors Theatre of Louisville (Kentucky); appeared in Beth Henley's "Crimes of the Heart"
- 1977: Reprised her stage role in L.A. production of "Vanities"
- 1977: Made TV debut on an episode of "The Love Boat"
- 1976: Off-Broadway debut as Joanne, one of the Texas Southern belles. in the three-character drama "Vanities"
- 1973: Stage debut as a duck in "Virginia Folk Tales" at Wayside Children's Theatre in Middletown, VA
- 1971: Feature film debut in bit role as a singer auditioning in Milos Forman's "Taking Off"; also wrote song "And Even Horses Had Wings" she performed in film; credited as Bobo Bates
- 1970: Moved to NYC to pursue career
- Raised in Memphis, TN
- Acted on stage in "The Art of Dining"




