Family
- father Nicholas Turturro: Died of lung cancer in 1988; came to US from Italy as a boy "knowing all the Fascist songs, and wound up a patriotic American serviceman who fought in D-Day"
- mother Katherine Turturro: Worked in a Navy yard during World War II; appeared in son's directing debut, "Mac" (1992)
- brother Ralph Turturro: Contributed artwork and storyboards to "Mac"
- brother Nicholas Turturro: Played John's brother in "Mo' Better Blues"; also appeared with brother in "Jungle Fever" and on stage in "Arturo Ui"; worked as doorman at St. Moritz hotel in New York; TV series regular on "NYPD Blue"
- cousin Aida Turturro: Played Grace in "True Love" (1989) and Eunice in 1992 Broadway revival of "A Streetcar Named Desire"
- son Amadeo Turturro: Born during shooting of "Barton Fink" c. 1990; named after artist Amedeo Modigliani; has appeared in "Illuminata" and "The Royal Tenenbaums"
- son Diego Turturro: Born in 2001
