Family
- grandmother Joanne Renfro: Raised Renfro
- grandfather : Died in 2001; in an interview in Details, (September 2001), Renfro described the man as a convict and a "drugstore cowboy"
- father Mark Renfro: Worked in a blueprint factory; divorced Renfro's mother in 1987; lived with Renfro and grandmother for a while before remarrying and moving out
- mother Angela: Divorced from Renfro's father in 1987; remarried; relocated from Tennessee to Michigan
- cousin Jesse Hasek: Lead singer of the band 10 Years
- son : After Renfro's death, it was revealed that he had a son who lived in Japan with his mother; the family have refused to name the boy or reveal any further details in order to protect his privacy
Companions
- Companion Gaby Hoffmann: Briefly dated in 1997
- Jennifer: dating in 2001
