- 2009: Played the wife of a woolly mammoth (voiced by Ray Romano) in the animated film "Ice Age: Dawn of the Dinosaurs"
- 2008: Co-starred with Dakota Fanning in the feature adaption of "The Secret Life of Bees"
- 2008: Co-starred with Diane Keaton and Katie Holmes in "Mad Money"
- 2007: Portrayed (also produced) an HIV-positive woman in the HBO movie "Life Support"; earned an Emmy nomination for Best Actress
- 2007: Cast as Motormouth Maybelle in the big screen version of the Tony-winning Broadway musical "Hairspray"
- 2006: Received a star on the Hollywood Walk of Fame (January)
- 2006: Co-starred as Emma Thompson's stern assisstant in the Marc Forster comedy, "Stranger Than Fiction"
- 2005: Starred in "Beauty Shop" a spin-off of the successful "Barber Shop" films
- 2004: Starred as a Beauty salon owner in "Barbershop 2: Back in Business"
- 2004: Made screenwritting debut with the comedy "The Cookout"; also produced
- 2004: Received a Grammy nomination for Best Jazz Vocal Album The Dana Owens Album
- 2003: Received grammy nomination for "Best Female Rap Solo Performance" for the song "Go Head"
- 2003: Co-starred with Steve Martin in the comedy "Bringing Down the House"
- 2003: Partnered with Curvations the lingerie line that applauds women with curves and confidence; also appeared as the face and body behind the new line of intimate apparel
- 2002: Cast in a supporting role in "Brown Sugar" starring Taye Diggs and Sanaa Lathan
- 2002: Cast as Matron Mama Morton in the musical feature adaptation of "Chicago"; earned Golden Globe and Oscar nominations
- 2002: Appeared in the CBS mini-series "Living With the Dead" about real-life psychic detective James Van Praagh
- 2002: Cast as Glenda the Good Witch in "The O.Z." a hip-hop TV adaptation of "The Wizard of Oz"
- 2001: Had recurring role as a psychic on the ABC sitcom "Spin City"
- 2000: Hosted the syndicated talk show "Queen Latifah"
- 1997: Profiled on "Intimate Portrait" (Lifetime)
- 1995: On July 16 the car in which she was a passenger was car-jacked in NYC; bodyguard was shot
- 1993: First substantial feature dramatic role, "My Life"
- 1993: Cast as a regular on the Fox sitcom "Living Single"; also wrote and performed the theme song
- 1991: First series guest spot, "The Fresh Prince of Bel-Air"
- 1991: First major supporting role, "House Party 2"
- 1991: Feature acting debut, Spike Lee's "Jungle Fever"
- 1990: TV debut, "Time Warner Presents the Earth Day Special" (ABC)
- 1989: Released her debut album, All Hail the Queen
- 1987: Had her demo tapes placed in circulation by a deejay friend
- Worked at a Burger King fast-food restaurant
- Trained in karate and use of firearms by her policeman father
- Worked as a cashier at the Wiz in Newark, New Jersey
- Was a power forward on two state championship basketball teams in high school
- Formed a rhyming group, Ladies Fresh, with two high school friends; won high school talent contest
- Grew up in East Orange, New Jersey
- "Discovered" by MTV host Fab 5 Freddy
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