Family
- father Dick Pfeiffer: heating and air conditioning contractor
- brother Rick Pfeiffer: older
- sister Michelle Pfeiffer: born in 1957
- sister Lori Pfeiffer: born in 1965
- mother Donna Pfeiffer:
Companions
- George Clooney:
- Ronnie Marquetee: dated briefly in 1995; committed suicide by shooting himself in front of Pfeiffer
