Family
- father Eric Thompson: Wrote and narrated the BBC children's series "The Magic Roundabout" in the 60s and 70s; died in 1982 at age 53
- mother Phyllida Law: Scottish; appeared with daughter in "Peter's Friends" (1992), "Much Ado About Nothing" (1993) and "The Winter Guest" (1997)
- sister Sophie Thompson: Born in 1962; best known for playing Stella Crawford in the BBC soap opera "EastEnders"
- daughter Gaia Romilly Wise: Born Dec. 4, 1999; father, Greg Wise
- child Tindyebwa Agaba: Informally adopted the 16-year-old Rwandan refugee with husband Wise
Companions
- Greg Wise: met during filming of "Sense and Sensibility"; together since 1995
- Hugh Laurie: dated while at Cambridge
