- 2009: Starred in the indie drama, "Downloading Nancy"
- 2008: Cast in the fantasy action film "The Mummy: Tomb of the Dragon Emperor"
- 2007: Cast in "The Jane Austen Book Club," as Jocelyn an independent, 50-something dog-breeder and organizer of the Club
- 2006: Played the wife of a rescued Port Authority officer in Oliver Stone's "World Trade Center"
- 2006: Joined Aaron Eckhart in the ensemble cast of "Thank You for Smoking"; the directorial debut of Jason Reitman
- 2005: Starred with Ethan Hawke and Laurence Fishburne in "Assault on Precinct 13"
- 2005: Co-starred with Viggo Mortensen in David Cronenberg's "A History of Violence"; earned a Golden Globe nomination for Lead Actress
- 2004: Cast opposite Johnny Depp in "The Secret Window"
- 2004: Cast in John Sayles’ political satire "Silver City"
- 2003: Played a Las Vegas casino waitress who falls for William H. Macy in "The Cooler"; earned Golden Globe and SAG nominations for Supporting Actress
- 2002: Cast as Bob Crane's second wife Patricia in director Paul Schrader's "Auto Focus"
- 2001: Starred in the IMAX movie "China: The Panda Adventure"
- 2001: Cast in the dark comedy "100 Mile Rule"
- 2000: Portrayed the bar owner in "Coyote Ugly"
- 2000: Cast as a sexy waitress who enjoys karaoke in "Duets"
- 1999: Co-starred with Mel Gibson in Brian Helgeland's "Payback"
- 1998: Played leading role opposite Ben Stiller in "Permanent Midnight"
- 1997: Had recurring role of Dr. Anna Del Amico on "ER"; made regular for the 1997-1998 season
- 1996: Co-starred with Scott Bakula in the short-lived CBS series "Mr. & Mrs. Smith"
- 1995: TV debut as a guest on the FOX comedy "Misery Loves Company"
- 1995: Made TV-movie debut in "The Commish: In the Shadow of the Gallows"
- 1992: Co-founded Harlem's Dream Yard Drama Project, a nonprofit arts and education program for urban kids
- Shot a few commercials in NYC, including one for Amstel Light
- Appeared in stage productions in NYC




