Family
- father Peter Gruffudd: Was headmaster at two Welsh comprehensive schools in South Wales, first at Ysgol Gyfun Llanhari and later at Ysgol Gyfun Rhydfelen
- mother Gillian Gruffudd:
- brother Alun Gruffudd: Born c. 1975
- sister Siwan Gruffudd: Born c. 1980
- daughter Ella Betsi Evans Gruffudd: Born Sept. 6, 2009; mother, Alice Evans
Companions
- wife Alice Evans: Met during the production of "102 Dalmatians" (2000); previously engaged to Olivier Picasso, the grandson of painter Pablo Picasso; married Sept. 14, 2007 in Los Cabos, Mexico
- Charlotte Hayward: met when both were students at RADA; no longer together
