Family
- daughter Tabitha Hodge Broderick: Twin of Marion; born June 22, 2009 by way of a surrogate
- daughter Marion Loretta Elwell Broderick: Twin of Tabitha; born June 22, 2009 by way of a surrogate
- sister Martha Broderick:
- sister Janet Broderick: Married Broderick and Parker on May 19, 1997
- father James Broderick: Played the father on the ABC TV show "Family" from 1976 to 1980; died of cancer in 1982 at age 55
- mother Patricia Broderick: After her death in 2003, her work was shown at the Tibor de Nagy gallery in New York
- son James Wilkie Broderick: Born Oct. 28, 2002; mother, Sarah Jessica Parker
Companions
- Companion Jennifer Grey: Met on the set of "Ferris Bueller's Day Off" (1986); were briefly engaged in 1987; Grey was a passenger in the car Broderick was driving, which caused a fatal collision, while they were vacationing in Northern Ireland
- wife Sarah Jessica Parker: Best known for her role as Carrie Bradshaw on the HBO series "Sex and the City"; met through Parker's brother, Timothy Britten Parker in 1992; married May 19, 1997 in a civil ceremony performed by Broderick's sister
- Helen Hunt: met during the filming of "Project X" (1987); no longer together
- Jennifer Grey: dated in the late 1980s; no longer together; Grey was a passenger in the car Broderick was driving that was involved in a fatal accident in Ireland in 1987
- Penelope Ann Miller: dated when they appeared on Broadway opposite one another in "Biloxi Blues" (1985)
- wife Sarah Jessica Parker: married May 19, 1997; together from c. 1992
