- 2009: Portrayed notorious Depression-era bank robber John Dillinger in Michael Mann's 1930s gangland flick "Public Enemies"
- 2007: Reprised role of Captain Jack Sparrow in "Pirates of the Caribbean: At World's End"
- 2007: Reteamed with Burton to play The Demon Barber of Fleet Street for the film adaptation of the musical, "Sweeny Todd"; earned an Oscar nomination for Best Actor in a leading role
- 2006: Reprised the role of Captain Jack Sparrow in Gore Verbinski's "Pirates of the Caribbean: Dead Man's Chest"; received a Golden Globe nomination for Best Actor in a Comedy or Musical
- 2005: Cast as Willy Wonka, in Tim Burton's remake of the classic tale "Charlie and the Chocolate Factory"; earned a Golden Globe nomination for Best Actor
- 2004: Portrayed 'Peter Pan' author J.M. Barrie in "Finding Neverland" also starring Kate Winslet; received Golden Globe, SAG and Academy Award nominations for Best Actor
- 2004: Played a writer who is accused of plagiarism by a strange man, who then starts haunting him in "The Secret Window"
- 2003: Starred in the blockbuster hit "Pirates of the Caribbean: The Curse of the Black Pearl"; earned Golden Globe and Academy Award nominations for Best Actor
- 2003: Played a sociopathic CIA agent in the Robert Rodriguez western feature "Once Upon A Time In Mexico"
- 2001: Cast as a British policeman with unorthodox means of tracking a serial killer in the thriller "From Hell"
- 2001: Portrayed American George Jung, one of the major cocaine traffickers for Columbian kingpin Pablo Escobar, in Ted Demme's "Blow"
- 2000: Reteamed with Terry Gilliam to play a modern-day ad executive whisked back in time in "The Man Who Killed Don Quixote"; shooting began in 2000 but was put on hold when leading actor Jean Rochefort suffered a double disc hernia
- 2000: Had two roles in Julian Schnabel's "Before Night Falls," a biopic of gay Cuban writer Reinaldo Arenas; portrayed an imprisoned drag queen with a gift for smuggling and a brutally officious army officer
- 1999: Reteamed with Burton for "Sleepy Hollow" starring opposite Christina Ricci
- 1999: Starred as corruptible rare-book dealer hired to find satanic texts in Roman Polanski's supernatural thriller "The Ninth Gate"
- 1999: Starred opposite Charlize Theron in the thriller "The Astronaut's Wife"
- 1999: Received star on the Hollywood Walk of Fame (November 16)
- 1998: Portrayed Raoul Duke in Terry Gilliam's adaptation of "Fear and Loathing in Las Vegas"; first film with Christina Ricci
- 1997: Feature directorial debut, "The Brave" reteamed him with Brando; also wrote and co-starred; premiered at the Cannes Film Festival; Iggy Pop wrote the score
- 1997: Earned some of the best reviews of his career as the title character in "Donnie Brasco"; based on the book about an FBI agent who infiltrated the Mob
- 1996: Starred as William Blake in Jim Jarmusch's post-modern Western "Dead Man"; film also featured Iggy Pop
- 1995: Formed the rock group P, making major label debut on Capitol Records
- 1995: Acted opposite Marlon Brando in "Don Juan DeMarco"
- 1995: Made first action film, John Badham's "Nick of Time"; cast as a mild-mannered accountant who becomes embroiled in an assassination scheme
- 1995: Purchased first home in Los Angeles; house once owned by Bela Lugosi
- 1994: Played infamous, cross-dressing, B-movie director "Ed Wood"; second film with Burton
- 1994: Directed the eight-minute short film "Banter" for DARE (Drug Abuse Resistance Education)
- 1993: Starred in the title role of "What's Eating Gilbert Grape"
- 1993: Impressively recreated silent-comedy routines of Charlie Chaplin and Buster Keaton in "Benny and Joon"
- 1993: Opened L.A. club, The Viper Room
- 1992: Appeared along with Jerry Lewis and Faye Dunaway in Emir Kusturica's "Arizona Dream"
- 1990: First hit movie, Tim Burton's "Edward Scissorhands" co-starring then-girlfriend Winona Ryder
- 1990: Headlined John Waters' "Cry-Baby" playing the Elvis-inspired, leather-clad title role; first film acting with Iggy Pop
- 1987: Began working with the Make-A-Wish Foundation
- 1987: Starred as a baby-faced undercover cop in TV series, "21 Jump Street" (Fox)
- 1986: TV-movie debut, "Slow Burn" (Showtime)
- 1986: Had small role in Oliver Stone's "Platoon"
- 1985: First screen lead, "Private Resort"
- 1985: TV acting debut in episode of "Lady Blue" (ABC)
- 1984: Introduced by his then-wife Lori Allison to actor Nicolas Cage, who helped arranged a meeting with an agent who set up audition for his feature acting debut in Wes Craven's "A Nightmare on Elm Street"; the director's daughter Jessica also played a part in convincing her father to cast Depp
- 1983: Moved to Los Angeles with band, The Kids; played lead guitar
- 1969: Moved to Miramar, Florida
- Sold ball-point pens by phone before he began acting
- Replaced the deceased Heath Ledger's character in, "The Imaginarium of Doctor Parnassus" (lensed 2008)
- Started own rock group at age 13; subsequently played in 15 other bands




