- 2009: Earned an Emmy nomination for his guest starring role on NBC's "30 Rock" as Milton Greene, Jack's biological father
- 2007: Co-starred in the boxing film "Resurrecting the Champ"
- 2005: Published his memoirs, Never Have Your Dog Stuffed: and Other Things I've Learned
- 2005: Starred in Joe Mantello's revival of David Mamet's play "Glengarry Glen Ross"; earned a Tony nomination for his role
- 2004: Joined the cast of NBC's White House drama "The West Wing" playing a Republican from California with presidential aspirations; earned Emmy (2005) and SAG (2006) nominations for Best Supporting Actor in a Drama Series
- 2004: Cast as Senator Ralph Owen Brewster in Martin Scorsese's "The Aviator" based on the life of legendary director and aviator Howard Hughes; earned an Oscar nomination for Best Supporting Actor
- 2001: Portrayed defense attorney Ernie Goodman in the Showtime original movie, "The Killing Yard"
- 2001: Played lead role of physicist Richard Feynman in the L.A. stage production of "Q.E.D."; reprised role in NYC
- 2001: Received 30th career Emmy nomination for the Showtime movie "Club Land"
- 1999: Had a recurring role on NBC's "ER" as a prominent surgeon in the early stages of Alzheimer's disease; earned an Emmy nomination for Outstanding Guest Actor
- 1998: Returned to Broadway co-starring with Alfred Molina and Victor Garber in "Art"
- 1998: Played Jennifer Aniston's brother-in-law in "The Object of My Affection"
- 1997: Appeared in Costa-Gavras' "Mad City" opposite Dustin Hoffman and John Travolta
- 1996: Made third film with Woody Allen, the romantic musical comedy "Everyone Says I Love You"
- 1996: Reprised stage role in CBS TV adaptation of "Neil Simon's 'Jake's Women'"
- 1994: Offered an uncharacteristically nasty turn in the based-on-fact drama "White Mile" (HBO)
- 1993: Portrayed scientist Robert Gallo in the acclaimed TV-movie "And the Band Played On" (HBO); received Emmy nomination
- 1993: Hosted the PBS series, "Scientific American Frontiers"
- 1993: Teamed again with Woody Allen for "Manhattan Murder Mystery"
- 1992: Returned to Broadway as star of Neil Simon's play "Jake's Women"
- 1991: Made London stage debut as the Stage Manager in Thornton Wilder's "Our Town"
- 1990: Last film (to date) as writer/director, "Betsey's Wedding"; also co-starred
- 1989: Received critical acclaim for the role of an egotistical director in Woody Allen's "Crimes and Misdemeanors"
- 1988: Helmed third film (also wrote and starred), "A New Life"
- 1986: Directed and wrote second film, "Sweet Liberty"
- 1984: Executive produced the short-lived CBS sitcom, "The Four Seasons" based film; also appeared in pilot
- 1981: Feature directing debut (also scripted), the ensemble "The Four Seasons"; again collaborated with Burnett who played his on screen spouse
- 1979: Feature screenwriting debut, "The Seduction of Joe Tynan"; also starred as the titular politician
- 1978: Teamed with Ellen Burstyn in Robert Mulligan's feature adaptation of "Same Time, Next Year"
- 1977: Portrayed convicted killer Caryl Chessman in the NBC TV-movie, "Kill Me If You Can"; earned an Emmy nomination
- 1975: Created and wrote pilot for the CBS sitcom, "We'll Get By"; also executive produced
- 1974: Co-directed and co-starred (with Carol Burnett) in the TV adaptation of the Broadway comedy "6 Rms Riv Vu" (CBS); earned an Emmy nomination for Best Actor
- 1972: TV-movie debut in "The Glass House" (ABC)
- 1972: Breakthrough role of Capt. Benjamin Franklin 'Hawkeye' Pierce in the TV adaptation of the 1970 film "M*A*S*H" (CBS); wrote 13 episodes and directed 32, including the show's 1983 2½ hour series finale "Goodbye, Farewell, and Amen"; earned 25 Emmy nominations for acting, writing and directing and 11 Golden Globe nominations
- 1968: Portrayed George Plimpton in the biopic "Paper Lion"
- 1967: Starred in the Broadway musical "The Apple Tree"; earned a Tony Award nomination
- 1964: First leading role on Broadway in "The Owl and the Pussycat"
- 1964: Cast as a series regular on the NBC political and social satire program, "That Was the Week That Was"
- 1963: Film acting debut in "Gone Are the Days"; repeating his role from the Broadway production "Purlie Victorious"
- 1963: Appeared in the Broadway play "Fair Game for Lovers"
- 1961: Co-starred in "Purlie Victorious" on Broadway
- 1956: Made New York stage debut as an understudy in "The Hot Corner"
- 1955: While in Europe studing abroad, performed with father on stage in the Rome production of "Room Service"
- 1953: Made theatrical debut at age 17, starring in "Charley's Aunt" in summer stock in Barnesville, Pennsylvania
- 1951: Performed Abbott-and-Costello-style comic sketches with his father at the Hollywood Canteen




