- 2008: Wrote and directed "The Spirit" from the newspaper comic book supplement of the same name created by Will Eisner
- 2007: "300" was adapted by director Zack Snyder into a highly successful film; was an executive producer
- 2005: Co-directed with Robert Rodriguez the film adaptation of his graphic series "Sin City"
- 1998: Wrote and illustrated, with painted colors by Varley, the graphic novel 300
- 1993: Scripted the film "RoboCop 3"
- 1992: First completely solo work, Sin City; wrote and drew the story in black and white to emphasize its film noir origins
- 1990: Wrote the screenplays for "RoboCop 2"
- 1986: Developed the groundbreaking four-issue miniseries Batman: The Dark Knight Returns; inked by Klaus Janson and colored by Lynn Varley
- 1983: Created the DC Comics' six-issue miniseries Ronin; first of many collaborations with his wife Lynn Varley
- 1983: During his run on Daredevil, Miller created the ninja mercenary Elektra
- 1980: Was an artist for Marvel comics' Daredevil; also began contributing to the story
- 1979: First gained attention from a two issue story for Marvel's Peter Parker, the Spectacular Spider-Man
- 1978: First published work in Gold Key Comics' The Twilight Zone
- 1978: Freelanced at DC Comics




