- 2009: Appeared in the film version of Michael Chabon's novel, "The Mysteries of Pittsburgh"
- 2008: Voiced Mulgrath in the fantasy feature "The Spiderwick Chronicles"
- 2008: Co-starred in the Ben Stiller directed action comedy "Tropic Thunder"
- 2006: Cast as a mentor in Victor Salva's "Peaceful Warrior"
- 2006: Voiced a bear named Vincent in the animated comedy "Over the Hedge" based on the comic strip by Michael Fry and T. Lewis
- 2004: Co-starred with Don Cheadle in Terry George's "Hotel Rwanda"; based on the true-life story of Paul Rusesabagina, a hotel manager who housed over a thousand Tutsis refugees during their struggle against the Hutu militia in Rwanda
- 2003: Cast as the father of scientist-turned-monster in Ang Lee's adaptation of the comic book "Hulk"
- 2003: Starred as a gambler in the comedy "The Good Thief"
- 2001: Reteamed with Rudolph for "Investigating Sex"
- 2000: Had featured role as a politician involved in a scandal in "Trixie"; helmed by Rudolph
- 2000: Returned to stage acting opposite Sean Penn in Sam Shepard's play "The Late Henry Moss"
- 2000: Cast as an American billionaire in the Merchant-Ivory "The Golden Bowl"; adapted from the Henry James novel
- 1999: Played a cross-dressing car salesman in "Breakfast of Champions" directed by Alan Rudolph
- 1998: Appeared in star-studded remake of "The Thin Red Line" directed by Terence Malick
- 1998: Won strong notices for his superb performance as a middle-aged, small-town man becoming unhinged in Paul Schrader's "Affliction"; also executive produced; received second Best Actor Oscar nomination
- 1997: Did a sexy, lovable-old-bear turn opposite Julie Christie in Alan Rudolph's "Afterglow"
- 1996: Starred in "Mother Night" the film adapted from the Kurt Vonnegut novel
- 1995: Played Thomas Jefferson in the Merchant-Ivory production "Jefferson in Paris"
- 1994: Cast as hard-driving college basketball coach in "Blue Chips"; scripted by Ron Shelton who also wrote "Under Fire"
- 1992: Starred opposite Susan Sarandon in "Lorenzo's Oil"
- 1991: Co-starred with Barbra Streisand (also directed) in "The Prince of Tides"; received Oscar nomination as Best Actor
- 1991: Reteamed with Scorsese for the remake of "Cape Fear"; played the role Gregory Peck created in 1962 original
- 1990: Found himself waist-deep in NYC police department corruption in Sidney Lumet's "Q&A"
- 1990: Reteamed with Debra Winger for the bomb "Everybody Wins"; Arthur Miller's first screenplay since "The Misfits"
- 1990: Re-teamed with Murphy to reprise their roles in "Another 48 Hours"
- 1989: Portrayed a New York artist in "Life Lessons" the Martin Scorsese-directed segment of the anthology film "New York Stories"; first screen collaboration Scorsese
- 1986: Gave memorable performance as a bum who wreaks havoc in the home of a rich couple in Paul Mazursky's "Down and Out in Beverly Hills"
- 1983: Portrayed Russell Price, a 30-year-old photographer covering the Nicaraguan revolution, in "Under Fire"; director Roger Spottiswoode also wrote "48 Hours" screenplay
- 1982: Starred opposite Debra Winger in "Cannery Row"
- 1982: Held his own opposite Eddie Murphy (in his screen debut) in "48 Hours"
- 1979: Delivered a Super Bowl-level performance as disillusioned pro wide receiver in "North Dallas Forty"
- 1978: Played drug-smuggling Vietnam vet in "Who'll Stop the Rain"; film adapted from Robert Stone's novel Dog Soldiers
- 1976: Gained attention for role as black sheep Tom Jordache in TV miniseries, "Rich Man, Poor Man" (ABC); earned Emmy nomination
- 1975: Feature film debut in "Return to Macon County"
- 1974: Appeared in TV pilot, "Winter Kill" (ABC)
- 1973: Moved to Los Angleles to reprise his Phoenix stage performance in William Inge's "The Last Pad" (Inge commited suicide four days before the play's opening night in LA); his performance won him an agent and some film and TV work
- 1973: TV debut in "The Framing of Billy the Kid" episode of "Griff" (ABC)
- 1971: Moved to New York City, appeared at Cafe La Mama
- 1968: Joined Old Log Theatre in Minneapolis, Minnesota
- 1963: Auditioned for the Pasadena Playhouse at age 23
- Moved to Phoenix, Arizona when parents separated; took Allen Dutton's photography course at Phoenix College
- Formed production company Kingsgate Films
- Began modeling for runway and print ads; his face appeared on the Clairol box for several years
- Joined Actors Inner Circle Theatre in Phoenix




