| Paris, Je T'aime (2007) | Actor |
| Chicago 10 (2007) | Actor |
| Clean (2006) | Starred as Albrecht Hauser |
| The Beautiful Country (2004) | Actor |
| This So-Called Disaster (2004) | Starred as Himself |
| Hotel Rwanda (2004) | Starred as Colonel Oliver |
| The Good Thief (2003) | Starred as Bob |
| The Hulk (2003) | Starred as Dr David Banner |
| Northfork (2003) | Starred as Father Harlan |
| The Golden Bowl (2001) | Starred as Adam Verver |
| Investigating Sex (2001) | Starred as Faldo, Producer |
| Trixie (2000) | Starred as Senator Drummond Avery |
| Breakfast of Champions (1999) | Starred as Harry Le Sabre |
| Simpatico (1999) | Starred as Vincent 'Vinnie'T Webb |
| Affliction (1998) | Starred as Wade Whitehouse |
| Night Watch (1998) | Starred as Inspector Thomas Cray |
| The Thin Red Line (1998) | Starred as Lieutenant Colonel Tall |
| Afterglow (1997) | Starred as Lucky 'Fix-It' Mann |
| U-Turn (1997) | Starred as Jake McKenna |
| Mother Night (1996) | Starred as Howard Campbell |
| Mulholland Falls (1996) | Starred as Hoover |
| Jefferson in Paris (1995) | Starred as Thomas Jefferson |
| Blue Chips (1994) | Starred as Pete Bell |
| I Love Trouble (1994) | Starred as Peter Brackett |
| I'll Do Anything (1994) | Starred as Matt Hobbs |
| Lorenzo's Oil (1992) | Starred as Augusto Odone |
| The Player (1992) | Starred as Himself |
| Cape Fear (1991) | Starred as Sam Bowden |
| The Prince of Tides (1991) | Starred as Tom Wingo |
| Another 48 Hours (1990) | Starred as Detective Jack Cates |
| Everybody Wins (1990) | Starred as Tom O'Toole |
| Q&A (1990) | Starred as Mike Brennan |
| Three Fugitives (1989) | Starred as Daniel Lucas |
| Farewell to the King (1989) | Starred as Sergeant Learoyd |
| Extreme Prejudice (1987) | Starred as Jack Benteen |
| Weeds (1987) | Starred as Lee Umstetter |
| Down and Out in Beverly Hills (1986) | Starred as Jerry Baskin |
| Grace Quigley (1985) | Starred as Seymour Flint |
| Teachers (1984) | Starred as Alex |
| Under Fire (1983) | Starred as Russell Price |
| 48 HRS. (1982) | Starred as Detective Jack Cates |
| Cannery Row (1982) | Starred as Doc |
| North Dallas Forty (1979) | Starred as Phillip Elliott |
| Heart Beat (1979) | Starred as Neal Cassady |
| Who'll Stop the Rain? (1978) | Starred as Ray Hicks |
| The Deep (1977) | Starred as David Sanders |
| Return to Macon County (1975) | Starred as Bo Hollinger |
| Arcadia Lost | Producer |
| Over the Hedge | Voice |
| The Way of the Peaceful Warrior | Starred as Socrates |
| Neverwas | Actor |
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Based on one of the most popular video game franchises in history. The...
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