- 2008: Directed the family drama "Rachel Getting Married" starring Anne Hathaway and Debra Winger; earned an Independent Spirit Award nomination for Best Feature
- 2008: Nominated for the 2008 Independent Spirit Award for Best Director (“Rachel Getting Married”)
- 2007: Helmed the documentary "Man from Plains," featuring Jimmy Carter as Carter promotes his book Palestine:Peace not Apartheid
- 2004: Directed a remake of the 1962 thriller "The Manchurian Candidate," based on the novel by Richard Condon
- 2002: Directed "The Truth About Charlie," a remake of the classic "Charade"
- 1998: Directed an adaptation of Toni Morrison's Pulitzer Prize-winning novel "Beloved"; starring and co-produced by Oprah Winfrey
- 1998: Directed the documentary of legendary rocker Robyn Hitchcock, "Storefront Hitchcock"
- 1997: Executive produced and helmed "Subway Car From Hell" segment of HBO's anthology movie "Subway Stories: Tales From the Underground"
- 1994: Provided the funding so that his wife's best friend, AIDS-stricken artist Juan Botas, could make his documentary "One Foot on a Banana Peel, the Other Foot in the Grave"
- 1993: Produced and directed "Philadelphia," a politically correct, look at the AIDS epidemic and American homophobia; Reverend Castle played Hanks' father; again collaborated with Zea and screenwriter Ron Nyswaner
- 1992: Directed "Cousin Bobby," a documentary of radical Harlem clergyman Robert Castle, the director's cousin
- 1991: Directed first blockbuster, "The Silence of the Lambs"; one of the few films to win all the major categories, including Best Picture and Best Director
- 1988: Directed the Mafia farce "Married to the Mob"; Byrne wrote the score; first collaboration with production designer Kristi Zea
- 1987: Directed "Swimming to Cambodia," Spalding Gray's monologue about his participation in the film, "The Killing Fields"
- 1986: Produced and directed the comedy thriller, "Something Wild"; Byrne contributed opening song
- 1985: Contributed a cameo to John Landis' "Into the Night"
- 1984: Shot outstanding concert film, "Stop Making Sense" featuring David Byrne and his band Talking Heads
- 1984: Credited as Rob Morton for his contributions to the screenplay of "Swing Shift"; also directed (executive producer Goldie Hawn took over final cut of film and hired another director to re-shoot parts of the film)
- 1982: Directed the PBS teleplay, "Who Am I This Time?" starring Susan Sarandon and Christopher Walken
- 1982: First credit as Rob Morton for his contributions to the screenplay of "Ladies and Gentlemen, The Fabulous Stains"
- 1981: Helped photograph Adam Brooks' independent film "Ghost Sisters"
- 1980: Re-teamed with Le Mat (as Melvin Dummar) in "Melvin and Howard"; first association with Jason Robards Jr. (as Howard Hughes)
- 1979: Directed the Hitchcockian suspense thriller "Last Embrace"
- 1978: Made TV directorial debut with "Murder Under Glass," an NBC TV-movie episode of the Peter Falk "Columbo" series
- 1978: Acted in the film "The Incredible Melting Man"
- 1977: First collaboration with actor Paul Le Mat, "Citizens Band/Handle With Care"
- 1974: Feature directing debut, "Caged Heat"; also wrote screenplay; first collaboration with director of photography Tak Fujimoto
- 1972: Re-teamed with Viola to make "The Hot Box"
- 1971: Debut as co-screenwriter, co-producer and second unit director, "Angels Hard as They Come"; directed by Joe Viola and produced by Corman
- 1970: First film credit as a musical coordinator on the Irwin Allen production "Sudden Terror/Eyewitness"
- 1968: Met and befriended Francois Truffaut, who was then publicizing "The Bride Wore Black" (1968) in NYC
- 1966: Sold films for Pathe Contemporary Films in NYC
- 1964: Introduced by his father to producer Joseph E. Levine who, pleased by Demme's review of "Zulu" (1964), hired him to write press releases
- 1959: Moved to with family to Miami, Florida at age 15 from New York
- Wrote for the exhibitor trade paper Film Daily
- While working in London, met producer-director Roger Corman
- Worked in the NY publicity department of United Artists
- Formed the production company, Clinica Estetico Ltd.
- Made 16mm short film, "Good Morning, Steve"




