Family
- grandfather Baron Karl von Schlebrugge: Maternal grandfather; jailed by Nazis in WWII for not betraying his Jewish business partners
- grandmother Brigit Holmquist: Maternal grandmother; famous Swedish model who posed in 1930 for the statue of a nude woman that still stands overlooking the harbor of Smygehuk in Sweden
- grandmother Elizabeth Farrar: Paternal grandmother
- brother Ganden Thurman: Born in 1971; director of Tibet House New York, which was co-founded by his father Robert Thurman
- brother Dechen Thurman: Born in 1973
- brother Mipam Thurman: Born in 1978
- daughter Maya Ray Thurman-Hawke: Born July 8, 1998; father, Ethan Hawke
- son Roan Thurman-Hawke: Born Jan. 15, 2002; father, Ethan Hawke
- half-sister Taya Thurman: Born in 1960; daughter from Robert Thurman's first marriage
- mother Nena Thurman: Born in 1941; popular model in the 1950s and 1960s; briefly married to LSD guru Timothy Leary from 1964-1966, after the two were introduced by Salvador Dalí; married Uma's father, Robert Thurman in 1967
- father Robert Thurman: Born in 1941; Tibetan-Buddhist scholar; teaches Indo-Tibetan Buddhist Studies at Columbia University in NYC; became the first Westerner to be ordained as a Tibetan monk in 1964; co-founder and president of the Tibet House New York; chosen by Time magazine as one of the 25 most influential Americans of 1997
- godfather Timothy Leary: An icon of 1960s counterculture and famous as a proponent of the therapeutic and spiritual benefits of LSD; coined and popularized the catch phrase "Turn on, tune in, drop out"
Companions
- Companion Phil Joanou: Dated briefly in 1988
- husband Ethan Hawke: married on May 1, 1998
- Timothy Hutton: on and off relationship; began during filming of "Beautiful Girls" (1995); no longer together
- Companion Andre Balazs: Began dating in December 2003, soon after her split with husband Ethan Hawke; ended their three-year, on-again, off-again relationship in March 2006
- Companion Arpad Busson: Began dating in July 2007; former partner of supermodel Elle Macpherson; announced engagement in June 2008
