- 2008: Played the title role in "Miss Pettigrew Lives for a Day"
- 2008: Joined an ensemble cast for the Coen's brothers' "Burn After Reading"
- 2008: Nominated for the 2008 Golden Globe Award for Best Performance by an Actress in a Motion Picture – Musical or Comedy ("Burn After Reading")
- 2006: Co-starred with Joan Cusack, Jennifer Aniston and Catherine Keener in director Nicole Holofcener's "Friends with Money"
- 2005: Re-teamed with Charlize Theron for the feature adaptation of MTV's cartoon "Aeon Flux"
- 2005: Co-starred with Charlize Theron in "North Country" a fictionalized account of the first successful sexual harassment case in the US; earned Oscar, Golden Globe and SAG nominations for Best Supporting Actress
- 2003: Played Diane Keaton's sister in Nancy Meyers' "Something's Gotta Give"
- 2002: Returned to the NYC stage opposite Willem Dafoe in "To You, the Birdie!"
- 2002: Co-starred in the drama "Laurel Canyon"; received an Independent Spirit Award nomination for best supporting female
- 2001: Played a straying spouse in the Coen brothers' modern noir "The Man Who Wasn't There"
- 2000: Protrayed an eccentric, overprotective mother in Cameron Crowe's "Almost Famous"; received a Best Supporting Actress Oscar nomination
- 2000: Co-starred as Michael Douglas' lover, a college chancellor, in "Wonder Boys"
- 1998: Portrayed Miss Clavell in "Madeline" the adaptation of a children's book series written by Ludwig Bemelmans
- 1998: Starred as Blanche Du Bois in an Irish production of "A Streetcar Named Desire"
- 1998: Returned to the New York stage co-starring with Billy Crudup in an Off-Broadway production of "Oedipus"
- 1997: Cast as a German doctor forced into an internment camp with other European women in Bruce Beresford's "Paradise Road"
- 1996: Earned critical praise for her performance as the pregnant police chief in the Coen brothers' "Fargo"
- 1996: Delivered a gem of a turn as Gus, a tough mechanic, in HBO's acclaimed "Hidden in America"
- 1995: Portrayed Patricia Arquette's sister in John Boorman's "Beyond Rangoon"
- 1995: Acted in Tommy Lee Jones' critically-acclaimed writing-directing debut, "The Good Old Boys" (TNT)
- 1993: Had featured role as Tim Robbins' girlfriend in Robert Altman's "Short Cuts"
- 1992: Played Pfeni, the youngest of three sisters, in the original Broadway production of "The Sisters Rosenzweig"
- 1990: Appeared uncredited in a bit part as a secretary in the Coens' "Miller's Crossing"
- 1990: Reteamed with Raimi on "Darkman"
- 1990: Co-starred in Ken Loach's controversial political thriller "Hidden Agenda"
- 1988: Earned a Tony nomination for her turn as Stella Kowalski in a Broadway revival of "A Streetcar Named Desire"
- 1988: Won substantial acclaim and a Best Supporting Oscar nomination for her turn in "Mississippi Burning"
- 1987: Co-starred in the CBS series, "Leg Work"
- 1987: Re-teamed with the Coen brothers for "Raising Arizona"; starred former roommate Holly Hunter
- 1985: Credited as Fran McDormand for Sam Raimi's "Crimewave"
- 1985: TV-movie acting debut, "Scandal Sheet" (ABC)
- 1984: Film acting debut, "Blood Simple"; first collaboration with the Coen brothers
- 1984: New York stage debut, Tina Howe's "Painting Churches"
- 1980: Stage acting debut in "Winterset: Four New American Plays" at Yale Repertory Theater
- Before age eight, moved frequently with family, before settling in Pennsylvania
- First professional stage role, "Trinidad" written by Jamaican poet Derek Walcott
- Moved to NYC, initially sharing a Bronx apartment with friend and fellow Yale graduate Holly Hunter




