Family
- father :
- mother :
- brother George Barkin: former editor in chief of The National Lampoon; older
- son Jack Byrne: born in October 1989; father, Gabriel Byrne
- daughter Romey Marion Byrne: born on November 18, 1992; father, Gabriel Byrne
Companions
- Companion Ralph Fiennes: rumored to be dating after being seen together in fall of 2006
- David Arquette: met on set of "Wild Bill"; born on September 8, 1971; no longer together
- husband Ronald Perelman: engaged as of spring 1999; married on June 28, 2000; his fourth marriage
- Val Kilmer: dated c. 1984
