- 2009: Returned to Broadway after more than 30 years as the elder ex-wife of a dying monarch, portrayed by Aussie actor Geoffrey Rush, in Eugene Ionesco's drama "Exit The King"
- 2008: Portrayed tobacco millionairess Doris Duke in the HBO film, "Bernard and Doris"; earned Emmy, Golden Globe and SAG nominations for Best Actress in a TV-movie
- 2008: Played Mom Racer in the Wachowski brothers' live action film adaptation of the 1960s Japanese series "Speed Racer"
- 2007: Co-starred opposite Tommy Lee Jones in Paul Haggis' "In the Valley of Elah"
- 2007: Played the evil queen in Disney's modern-day animation and live-action fairy tale, "Enchanted"
- 2006: Guest-starred in several episodes of Denis Leary's FX drama "Rescue Me"
- 2005: Co-starred as James Gandolfini's wife in "Romance & Cigarettes" directed by John Turturro; film released theatrically in 2007
- 2005: Played Orlando Bloom's mother in Cameron Crowe's drama "Elizabethtown"
- 2004: Starred opposite Jude Law in "Alfie" a remake of the 1966 film which starred Michael Caine
- 2004: Cast as Richard Gere's wife in "Shall We Dance?" a remake of the 1996 Japanese film
- 2002: Co-starred with Goldie Hawn in "The Banger Sisters"
- 2002: Played the title character's mother in "Igby Goes Down"; received a Golden Globe nomination for Best Supporting Actress
- 2002: Co-starred opposite Dustin Hoffman in "Moonlight Mile"
- 2001: Voiced the dog Ivy in the feature "Cats & Dogs"
- 2001: Made guest appearance in an episode of "Friends" (NBC), playing a soap opera actress; received Emmy nomination
- 2000: Had cameo role as painter Alice Neel in "Joe Gould's Secret," directed by Stanley Tucci
- 2000: Provided the voice for Coco La Bouche in the animated film "Rugrats in Paris - The Movie"
- 1999: Starred as a single mother of a teenager in Wayne Wang's "Anywhere But Here"
- 1999: Received a star on the Hollywood Walk of Fame
- 1999: Made cameo appearance in Robbins' feature "The Cradle Will Rock"
- 1998: Cast as a movie star married to Gene Hackman who calls upon old friend detective Paul Newman for assistance in Robert Benton's "Twilight"
- 1998: Co-starred with Ed Harris and Julia Roberts in the comedy-drama "Stepmom"; also served as executive producer
- 1996: Provided the voice of the Spider for "James and the Giant Peach"
- 1995: Starred in Robbins' "Dead Man Walking" opposite Sean Penn; finally won Oscar as Best Actress; Robbins' nomination as Best Director made them the first couple since Cassavetes and Rowlands to be jointly nominated for their work together
- 1994: Picked up a fourth Best Actress Oscar nomination for her turn as a non-nonense Southern attorney in "The Client"
- 1994: Portrayed the matriarch of the March family in Gillian Armstrong's "Little Women"
- 1992: Reteamed with Miller for "Lorenzo's Oil," earning her third Best Actress Academy Award nomination
- 1992: Played small role in Robbins' feature directing debut, "Bob Roberts"
- 1991: Co-starred with Geena Davis in the female buddy film, "Thelma & Louise," directed by Ridley Scott; earned second Best Actress Oscar nomination
- 1991: Made cameo appearance as herself in Robert Altman's "The Player," starring Robbins
- 1990: Portrayed older waitress who becomes involved with younger yuppie James Spader in "White Palace"
- 1988: Met companion Tim Robbins while co-starring in hit comedy "Bull Durham"
- 1987: First film with director George Miller, "The Witches of Eastwick"
- 1985: Starred as a housewife investigating a murder in the comedy-drama "Compromising Positions"; was pregnant with first child during filming which was noticably visible in some scenes
- 1985: Co-starred as Edda Ciano, the dictator's daughter in the HBO miniseries "Mussolini: The Decline and Fall of Il Duce"
- 1983: Love scene with Catherine Deneuve in Tony Scott's "The Hunger" created a minor furor
- 1982: Starred opposite Christopher Walken in the acclaimed PBS drama "Who Am I This Time?"
- 1982: Acted with John Cassavetes and wife Gena Rowlands in Paul Mazursky's "Tempest," loosely based on Shakespeare's play
- 1980: Off-Broadway debut in "A Coupla White Chicks Sitting Around Talking"
- 1980: Reteamed with Malle for "Atlantic City"; earned first Best Actress Oscar nomination playing a young casino employee who falls for older Burt Lancaster
- 1978: First film with director Louis Malle, "Pretty Baby," playing Brooke Shields' prostitute mother
- 1975: Co-starred as Janet in cult hit "The Rocky Horror Picture Show"
- 1975: Was leading lady to Robert Redford in "The Great Waldo Pepper"
- 1974: Played the fictionalized heroine in the TV dramatization "F. Scott Fitzgerald and the Last of the Belles" (ABC)
- 1972: Acted on the daytime soap "Search for Tomorrow"
- 1972: Broadway debut as Tricia Nixon in Gore Vidal's "An Evening With Richard Nixon and . . ."
- 1970: Screen debut in "Joe"; had accompanied then-husband Chris Sarandon to his audition for the film; she was hired instead
- 1970: First regular TV role, appeared in the ABC daytime soap, "A World Apart"
- Began career as a model with the Ford Agency
- Born in Jackson Heights, Queens and raised in Metuchen, New Jersey
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