Wild Hogs (2007)

A group of middle-aged friends decide to rev up their routine suburban lives with a freewheeling motorcycle trip. Taking a long dreamed-of breather from their stressful jobs and family responsibilities, they can't wait to feel the freedom of the open road. When this mismatched foursome, who have grown far more used to the couch than the saddle, set out for this once-in-a-lifetime experience, they encounter a world that holds far more than they ever bargained for. The trip begins to challenge their wits and their luck, especially during a chance run-in with a real-life biker gang.

Official website: http://www.wildhogsmovie.com/