Titan A.E. (2000)

The year is 3028. Mankind has conquered space, and even though it was routine to travel to the farthest galaxies, humans always thought that Earth would be home. However, with mankind's new freedom comes new enemies, forcing Earth to prepare for an attack by the Drej, a vicious alien race. In a little more than an instant, Earth is gone. The human race barely escapes with its greatest treasure, a magnificent ship christened the Titan. It is an epic journey that begins after Earth ends...