Darkwolf (2003)

Forced to take over an investigation involving werewolves, an LAPD Detective is led to the trail of one specific hybrid werewolf. This half-humnan-half beastis in LA to find the next matriarch of the pure-bred werewolves so that he can mate with her and continue the werewolf lineage. A young waitress becomes his target and the cop must find a way to rescue her and ultimately the entire human race who will become endangered if the mating occures.